تسجيل الدخول

تسجيل

ribosome P antibodies (Ribosomal P Ab, Anti–ribosome P antibodies)

المؤلف:  Kathleen Deska Pagana, Timothy J. Pagana, Theresa Noel Pagana.

المصدر:  Mosbys diagnostic and laboratory test reference

الجزء والصفحة:  15th edition , p787

2025-08-26

728

 Type of test Blood

 Normal findings

 Negative

Test explanation and related physiology

 This antibody test should not be confused with the antiextractable nuclear antibodies (antiribonucleoprotein antibody). Ribosome P antibodies are used as an adjunct in the evaluation of patients with lupus erythematosus (LE). Antibodies to ribosome P proteins are considered highly specific for LE and have been reported in patients with central nervous system (CNS) involvement (i.e., lupus psychosis). This antibody is therefore an aid in the differential diagnosis of neuropsychiatric symptoms in patients with LE. Because patients with LE may manifest signs and symptoms of CNS diseases, including neuropsychiatric symptoms, the presence of antibodies to ribosome P protein may be useful in the differential diagnosis of such patients. Most patients with LE do not have detectable levels of antibodies to ribosome P protein. But when they do, CNS involvement should be considered possible.

Procedure and patient care

• See inside front cover for Routine Blood Testing.

 • Fasting: no

• Blood tube commonly used: red

 • Check the venipuncture site for infection. Patients with autoimmune disease have compromised immune systems.

Abnormal findings

 Increased levels

- Lupus erythematosus