Type of test miscellaneous

Normal findings

Change in hydrogen < 20 ppm

Methane peak > 10 ppm

Test explanation and related physiology

 Small intestinal bacterial overgrowth (SIBO) is characterized by excessive bacteria or the presence of atypical microbiota in the small intestine. This breath test relies on measurement of gases produced by bacteria in the intestine—hydrogen (H2 ) and methane (CH4 )—after ingestion of lactulose in a fasting state. Lactulose is not absorbed by the intestines. Hydrogen gas is exclusively produced by colonic bacteria as a result of fermentation of the lactulose. In SIBO, the abnormal presence of abundant bacteria in the small intestine ferment the malabsorbed lactulose resulting in elevated concentration of exhaled hydro gen. An abnormal rise of hydrogen in the first 90 minutes of testing is positive for SIBO. Elevated exhaled methane is abnormal and is common in patients with irritable bowel disease, chronic constipation, or overeating. CO2 is routinely measured to deter mine sample integrity.

Conditions commonly associated with SIBO include irritable bowel syndromes, inflammatory bowel disease, celiac disease, diabetes, and obesity. These patients commonly complain of bloating, gas, pain, diarrhea, constipation, muscle pain (fibromyalgia), and bad breath. Bacterial overgrowth can also be identified by analyzing small intestinal fluid samples during enteroscopy.

In preparation for this test, the patient must wait at least 2 to 4 weeks after colonoscopy or barium enema. No antibiotics, bismuth containing agents, probiotics, stool softeners, laxatives, or antacids should be administered in that same time frame.

Interfering factors

• Patients with lactose intolerance or diseases of maldigestion may have increased levels.

* The use of antibiotics, laxatives, antacids, or probiotics may decrease levels. Before

* Explain the procedure to the patient. Inform the patient that multiple breath samples will be needed.

* Instruct the patient to fast for 12 hours before testing.

* Tell the patient to avoid smoking, including second-hand smoke, for at least 1 hour before or at any time during the breath test.

 During

• Provide a specified dose of lactulose usually diluted in 8oz of water.

• Collect breath samples at 20 minute intervals up to 60 to 120 minutes.

After

 • Indicate actual time of the breath sample and the amount of time after ingestion of the sample.

• Immediately send test specimens to the laboratory.

Abnormal findings

- Small bowel bacterial overgrowth

اخر الاخبار

اخبار العتبة العباسية المقدسة

جامعة أم البنين (عليها السلام) الإلكترونية تعلن فتح باب التسجيل للدراسات التبليغية والقرآنية

مستشفى الكفيل يعتمد أحدث التقنيات العالمية في عمليات زراعة القوقعة

مركز السيد جعفر الحلي يستقبل مدير صحة كربلاء للاطّلاع على خدماته المقدّمة للزائرين

قسم الشؤون الفكريَّة يقدِّم ندوة ثقافية لوفد شبابي من الموصل

المزيد

الآخبار الصحية

حالة صحية شائعة قد تُخفي "إنذارا مبكرا" للإصابة بالسرطان !

"أوميغا 3" صديق القلب.. هل يربك سكر الدم؟

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دراسة: محاولة متعمدة لنشر الإنفلونزا تنتهي بـ"مفاجأة"

المزيد

الآخبار التكنلوجية

سلامة الأطفال: سبع قواعد ذهبية للركوب الآمن بالسيارة

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"ميتا" توقف وصول المراهقين إلى شخصيات الذكاء الاصطناعي ؟

المزيد

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