تسجيل الدخول

تسجيل

Alcaligenes, Bordetella (Non-pertussis), Comamonas, and Similar Organisms : Pathogenesis and Spectrum of Disease

المؤلف:  Patricia M. Tille, PhD, MLS(ASCP)

المصدر:  Bailey & Scotts Diagnostic Microbiology

الجزء والصفحة:  13th Edition , p359-360

2026-05-17

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Identifiable virulence factors are not known for most of the organisms listed in Table1. However, because infections usually involve exposure of compromised patients to contaminated materials, most of these species are probably of low virulence. Among the environmental organisms listed, Achromobacter spp. are most frequently associated with various infections, including bacteremia, meningitis, pneumonia, and peritonitis. They also have been implicated in outbreaks of nosocomial infections. Achromobacter piechaudii has been isolated from pharyngeal swabs, wounds, blood, and ear discharge. Achromobacter xylosoxidans increasingly has been recovered from patients with cystic fibrosis. However, it is unclear whether the organism is implicated in causing clinical disease in patients with cystic fibrosis or whether it simply colonizes the respiratory tract. A. denitrificans has been recovered from urine, prostrate secretions, the buccal cavity, pleural fluid, and eye secretions. A. faecalis has been isolated from a wide range of clinical specimens and has been identified in bacteremia, ocular infections, pancreatic abscesses, bone infections, urine, and ear discharge. Comamonas spp. have been identified in cases of endocarditis, meningitis, and catheter-associated bacteremia. They have also been recovered from sputum in patients with cystic fibrosis. Other organisms, such as O. urethralis and O. ureolytica have been isolated predominantly from the human urinary tract. Pseudomonas alcaligenes and Pseudomonas pseudoalcaligenes rarely have been identified in clinical samples.

Table1. Pathogenesis and Spectrum of Disease