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Laboratory approaches to drug testing in DUID cases

المؤلف:  Sue Jickells , Adam Negrusz (Editors)

المصدر:  Clarkes Analytical Forensic Toxicology

الجزء والصفحة:  319

2026-10-28

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Laboratory approaches to drug testing in DUID cases

After a subject has been arrested for suspected driving while impaired through drugs, the sample that is taken and sent to the testing laboratory should be subject to a broad screen for common drugs relevant to the patterns of recreational drug use in the jurisdiction, as well as for common CNS-acting prescription and over-the-counter drugs. Most laboratories begin with an immunoassay screen. These assays are often class-specific rather than drug-specific, and their value is more to rule out the presence of certain drug classes than to provide a comprehensive test. Toxicologists should also be sensitive to the fact that immunoassays will not detect all types of drugs present, may produce different intensities of response to members of the same drug class and may fail to identify completely important members of a class of drugs. Immunoassay tests should, wherever possible, be supplemented by chromatographic tests to include as many of the locally relevant drugs as possible. Without this, the possibility of failing to identify a drug or metabolite that has caused impairment is significant.