تسجيل الدخول

تسجيل

Tablets

المؤلف:  Sue Jickells , Adam Negrusz (Editors)

المصدر:  Clarkes Analytical Forensic Toxicology

الجزء والصفحة:  p324-325

2026-10-28

36

Tablets

Tablets are compressed dosage forms that contain both active ingredients and inactive materials called excipients, which include diluents, adhesives, binders, fillers, lubricants, disintegrants and colours. Tablets need to be strong enough to withstand transport and handling, yet still disintegrate and release the active ingredients when consumed. The behaviour of the tablet depends on the production methods, the various excipients and their effect on the active ingredient. The physical form of the active ingredient (particle size) and the particular salt are also important.

The identification of a tablet is usually based on the physical appearance or the analytical determination of the active drug and seldom depends upon the nature of the excipients. However, examination of the gastric contents, after gastric lavage (now less favoured) or at post mortem, with a polarising microscope for the presence of starch granules may indicate the recent consumption of tablets or capsules.