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Date: 25-11-2019
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Date: 10-5-2019
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Carboxylic acids react with thionyl chloride (SOCl2) to form acid chlorides. During the reaction the hydroxyl group of the carboxylic acid is converted to a chlorosulfite intermediate making it a better leaving group. The chloride anion produced during the reaction acts a nucleophile.
Earlier we saw that primary and secondary alcohols react with PBr3 to afford the corresponding alkyl bromide. In a similar fashion acid bromides can be formed from the carboxylic acid.
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